Introduction:
The bladder neck and trigone harbor morphologically distinct smooth muscle fibers and innervation. Treatment of bladder tumors at these locations is generally believed to lead to higher morbidity following transurethral resection of bladder tumor (TURBT). Yet, literature systematically examining the influence of tumor location on postoperative recovery is largely lacking. Thus, we sought to quantitatively describe the severity and duration of symptoms and functional recovery according to tumor resection location for patients undergoing TURBT utilizing an ecological momentary symptom assessment platform.
Methods:
Patients scheduled for TURBT were invited to enroll in a text-messaged based education and ecological momentary symptom assessment platform to measure patient report outcomes. Patients were surveyed 7 days before surgery and on postoperative days 1, 2, 3, 5, 7, 10, and 14. Patients were asked to report the following using a 5-point Likert scale: dysuria, urinary frequency, urinary urgency, overall pain, ability to empty bladder, ability to work, ability to sleep, overall quality of life, and overall perceived subjective recovery from surgery. Hematuria was reported using a color scale. Patients whose resections included the bladder neck and/or trigone were compared with those whose resections did not. Patients with significant postoperative complications were excluded. The primary outcomes of interest were time to return to baseline reported symptoms in each domain, which was examined with cumulative incidence function.
Results:
144 patients were included in this analysis, of which 60 patients underwent TURBT that involved the trigone or bladder neck and 84 involving locations elsewhere in the bladder. Groups were similar in age, sex, total area of resection, indication, and use of a catheter postoperatively. We did not detect a significant difference between groups in time to recovery in any symptom domain. For both groups, recovery was overall rapid with 70% of patients reporting ≥ 4/5 for overall subjective recovery on postoperative day 2 and 80% on POD 3. Patients with resections including bladder neck or trigone reported less hematuria on POD 1 (22% vs. 37% p=0.18) with similar rates on POD 3 (26% vs 23%, p=1.0) and thereafter.
Conclusion:
Patients who undergo TURBT of the bladder neck or trigone experience a similar postoperative course regarding patient-reported urinary symptoms, functional outcomes, and quality of life when compared to patients who undergo resection of other bladder locations. The majority of patients report rapid recovery from surgery on POD 2 regardless of bladder tumor location.
Funding: N/A
Image(s) (click to enlarge):
BLADDER TUMOR LOCATION DOES NOT AFFECT POSTOPERATIVE RECOVERY: A REAL-WORLD ASSESSMENT EMPLOYING AN ECOLOGICAL MOMENTARY SYMPTOM ASSESSMENT PLATFORM
Category
Bladder Cancer > Non-Muscle Invasive Bladder Cancer
Description
Poster #74
Thursday, Dec 2
10:00 a.m. - 11:00 a.m.
Bladder 4
Presented By: Alberto A. Castro Bigalli
Authors:
Jared Schober
Alberto A. Castro Bigalli
Evan Bloom
Ryan Barlotta
Jennifer Lee
Seyed Behzad Jazayeri
Kevin B. Ginsburg
Mengying Deng
Elizabeth Handorf
David Y T Chen
Richard Greenberg
Marc Smaldone
Rosalia Viterbo
Robert Uzzo
Andres Correa
Alexander Kutikov
Marshall Strother